Dimethyl malonate

Catalog	ACM108598
CAS	108-59-8
Structure
Description	Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis.
Synonyms	2,2-Dimethylpropanedioate
IUPAC Name	Dimethyl propanedioate
Molecular Weight	132.11
Molecular Formula	C5H8O4
Canonical SMILES	O=C(OC)CC(OC)=O
InChI	InChI=1S/C5H8O4/c1-8-4(6)3-5(7)9-2/h3H2,1-2H3
InChI Key	BEPAFCGSDWSTEL-UHFFFAOYSA-N
Boiling Point	180-181 °C
Melting Point	-62 °C
Flash Point	194 °F
Purity	95%+
Density	1.156 g/mL at 25 °C(lit.)
Solubility	water, 9.951e+004 mg/L @ 25 °C (est)
Appearance	Colorless clear oily liquid (est)
Storage	Pure form-20°C,3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Exact Mass	132.04225873
Monoisotopic Mass	132.04225873
Physical State	Liquid
Refractive Index	n20/D 1.413(lit.)
Storage Conditions	Below +30 °C
Topological Polar Surface Area	52.6 Ų