Triacetin

Catalog	ACM102761-1
CAS	102-76-1
Structure
Description	The triglyceride 1,2,3-triacetoxypropane is more generally known as triacetin and glycerin triacetate. It is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride. It is a colorless, viscous and odorless liquid.
Synonyms	1,3-Diacetyloxypropan-2-yl acetate
IUPAC Name	2,3-Diacetyloxypropyl acetate
Molecular Weight	218.2
Molecular Formula	C9H14O6
Canonical SMILES	CC(=O)OCC(COC(=O)C)OC(=O)C
InChI	InChI=1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3
InChI Key	URAYPUMNDPQOKB-UHFFFAOYSA-N
Boiling Point	258-260 °C(lit.)
Melting Point	3 °C(lit.)
Flash Point	300 °F
Purity	99%+
Density	1.16 g/mL at 25 °C(lit.)
Solubility	Moderately soluble in water, soluble in organic solvents
Appearance	Clear colorless liquid
Application	Triacetin serves a versatile role across multiple industries primarily due to its unique chemical properties. It is a triglyceride formed by the acetylation of glycerol's three hydroxy groups, resulting in a colorless, viscous liquid with a slightly fatty odor. Known chemically as glyceryl triacetate, triacetin is predominantly employed as a hydrophilic plasticizer in the coating of capsules, tablets, beads, and granules, enhancing the flexibility and durability of these materials. Moreover, it finds application in cosmetics, perfumery, and the food industry as an effective solvent and fixative for perfumes and flavors. Triacetin also exhibits fungistatic properties because it releases acetic acid upon hydrolysis by skin esterases, which makes it useful in treating minor dermatophyte infections. This release of acetic acid, while beneficial, is self-limiting due to the inhibition of these enzymes at lower pH levels. Through its multifaceted functionality, triacetin effectively contributes to various formulations, offering enhanced performance and stability.
Storage	Sealed in dry, room temperature
Exact Mass	218.07903816
Monoisotopic Mass	218.07903816
Odor	Slightly fatty odor
Physical State	Liquid
Refractive Index	n25/D 1.429-1.431(lit.)
Storage Conditions	Dry place,Room Temperature
Topological Polar Surface Area	78.9 Ų