Cooling Agent WS-12

WS-12, a derivative of menthol, is an effective TRPM8 agonist and acts as a cooling agent. It strongly activates TRPM8 at low micromolar concentrations, exhibiting higher potency and efficacy than menthol. Additionally, it provides one of the strongest initial cooling effects and significantly longer lasting effects compared to cooling agents such as WS-3, WS-5, and WS-23.

Product detail

Characteristics

• Long-lasting effect: It has a strong cooling sensation and can release and prolong the cooling effect, which can last for more than 30 minutes.
• Good compatibility: Excellent compatibility with other flavors, can enhance the effect of them. It can also be used in combination with other cooling agents.
• Non-irritating effect: It is non-irritating to the skin and mucous membranes and is suitable for products with sensitive skin.
• Low dosage: 30-100 mg/kg can achieve strong cooling effect.

Applications

• Daily necessities: Commonly used in toothpaste, mouth freshener, mosquito repellent and other products to provide users with a sense of coolness and enhance the attractiveness of the product.
• Cosmetics: It can be used as a cooling agent for sunscreen, masks, lipsticks, and so on, to add a fresh mint flavor and enhance the experience of using the product.
• Foodstuffs: It can be used in all kinds of foodstuffs, such as chewing gum, beverage, chocolate, ice cream, to make the food taste more refreshing.
• Flavoring products: It can be used in soap and detergent flavors such as rose, bay leaf, lavender to enhance and intensify the aroma.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.