Methyl Salicylate

Catalog	ACM119368
CAS	119-36-8
Structure
Description	This product has anti-inflammatory and analgesic effects and is widely used in joint muscle analgesic ointment, tincture and oil. It is also used as solvent and various intermediates in the manufacture of pesticides, fungicides, polishing agents, copper resistant agents, spices, food, cosmetics, toothpaste, coatings, inks and fiber dye AIDS.;
Synonyms	O-Hydroxybenzoic acid methyl ester
IUPAC Name	Methyl 2-hydroxybenzoate
Molecular Weight	152.15
Molecular Formula	C8H8O3
Canonical SMILES	COC(=O)C1=CC=CC=C1O
InChI	InChI=1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3
InChI Key	OSWPMRLSEDHDFF-UHFFFAOYSA-N
Boiling Point	222 °C
Melting Point	-8--7 °C
Flash Point	226 °F
Purity	99%
Density	1.174 g/mL at 25 °C(lit.)
Solubility	less than 1 mg/mL at 66° F (NTP, 1992);Slightly soluble;0.05 M;0.7 mg/mL at 30 °C;SOL IN CHLOROFORM, ETHER; MISCIBLE WITH ALC, GLACIAL ACETIC ACID;SOL IN DIETHYL ETHER;SOLUBLE IN MOST COMMON ORGANIC SOLVENTS;Sol in water: 0.74%w @ 30 °C;0.7 mg/mL at 30 °C;Solubility in water, g/100ml at 20 °C: 0.07;slightly soluble in water; soluble in organic solvents, oils;miscible at room temperature (in ethanol)
Appearance	Oil
Application	Methyl salicylate serves multiple purposes across different industries due to its diverse properties. Primarily known as the main component of wintergreen oil, it is a colorless liquid with a distinct wintergreen aroma. It can be naturally extracted from several essential oils and fruits or synthesized via the esterification of salicylic acid with methanol. This compound plays several roles: as a flavoring agent, a metabolite, and an insect attractant. It finds significant use in creating fragrances, particularly in liniments and ointments used for their analgesic and anti-inflammatory effects, such as treating rheumatoid arthritis, low back pain, and muscle pain. Methyl salicylate is widely employed in the formulation of food flavors like strawberry and vanilla, adding sweetness to products like soft drinks and beer, and it is recognized as GRAS by FEMA and permissible in certain quantities by health authorities. Industrially, it functions as a preservative, pesticide, polish, and even a component in paints and inks. Despite its versatility, the compound is used cautiously in dermatological preparations due to its potential to cause local irritation when absorbed through the skin.
Exact Mass	152.047344113
Monoisotopic Mass	152.047344113
Odor	LIQUID HAVING THE CHARACTERISTIC ODOR OF WINTERGREEN
Physical State	Liquid
Refractive Index	n20/D 1.536(lit.)
Storage Conditions	Inert atmosphere,Room Temperature
Topological Polar Surface Area	46.5 Ų